師資
基本概況
李職秀博士，公共衛(wèi)生及應(yīng)急管理學(xué)院副教授（研究員），博士生導(dǎo)師。主要研究方向?yàn)槊庖呒膊〉嚷『蛷?fù)雜疾病的致病機(jī)理，早期診斷和精準(zhǔn)干預(yù)，以及傳染性疾病疫苗的開(kāi)發(fā)。曾主持和參與多項(xiàng)澳大利亞國(guó)家級(jí)、州政府級(jí)和企業(yè)科研項(xiàng)目。在Nature Genetics, Annals of the Rheumatic Diseases, PLos Genetics, Nature Reviews Rheumatology, Annal Review of Biophysics等權(quán)威SCI雜志發(fā)表論文40余篇 ?，F(xiàn)為Frontiers in Immunology 雜志客座編輯。曾擔(dān)任Nature Genetics, Nature Communications, Arthritis & Rheumatology, JAMA Network Open等多個(gè)SCI期刊審稿專(zhuān)家。曾任澳大利亞、英國(guó)和法國(guó)等國(guó)際基金會(huì)的通訊評(píng)審。多次在American College of Rheumatology年會(huì)，亞太風(fēng)濕病學(xué)會(huì)聯(lián)盟大會(huì)（APLAR）等國(guó)際會(huì)議上做大會(huì)報(bào)告和口頭學(xué)術(shù)報(bào)告，獲得2019 APLAR最佳摘要獎(jiǎng)。為國(guó)際強(qiáng)直性脊柱炎遺傳學(xué)聯(lián)盟（International Genetics of Ankylosing Spondylitis，IGAS）成員。
研究方向
1． 免疫疾病等慢病和復(fù)雜疾病的遺傳和非遺傳病因
2． 強(qiáng)直性脊柱炎等疾病的早期診斷，精準(zhǔn)干預(yù)和管理，以及相關(guān)方法的開(kāi)發(fā)
3． 針對(duì)重大傳染性疾病和病毒的精準(zhǔn)疫苗設(shè)計(jì)
工作經(jīng)歷
2023.12-至今 南方科技大學(xué)，公共衛(wèi)生與應(yīng)急管理學(xué)院，副教授
2023.06-2023.12 南方科技大學(xué)，公共衛(wèi)生與應(yīng)急管理學(xué)院，助理教授
2018-2022 昆士蘭科技大學(xué) Vice-Chancellor Research Fellow
2016-2018 昆士蘭科技大學(xué) 博士后
2014-2016 昆士蘭大學(xué) 博士后
教育經(jīng)歷
2009-2015 印第安納大學(xué) 信息學(xué)院 博士
2005-2009 中國(guó)科學(xué)技術(shù)大學(xué) 生命科學(xué)院 學(xué)士
代表性論文（#共同一作，*通訊作者）
1. Li, Z., McRae, A. F., Wang, G., et al. Genotype by sex interactions in ankylosing spondylitis. Nat. Genet. 55, 14–16 (2023).
2. Li, Z., Khan, M. K., Linden, S. M. van der, et al. HLA-B27, axial spondyloarthritis and survival. Ann. Rheum. Dis. (2023) doi:10.1136/ard-2023-224434.
3. Li, Z., Linden, S. M. van der, Khan, M. A., et al. Heterogeneity of axial spondyloarthritis: genetics, sex and structural damage matter. RMD Open 8, e002302 (2022).
4. Williams, C. J#., Li, Z.#, Harvey, N#., et al. Genome wide association study of response to interval and continuous exercise training: the Predict-HIIT study. J. Biomed. Sci. 28, 37 (2021).
5. Li, Z., Wu, X., Leo, P. J., et al. Polygenic Risk Scores have high diagnostic capacity in ankylosing spondylitis. Ann. Rheum. Dis. 80, 1168–1174 (2021).
6. Wang, G., Kim, T.-H., Li, Z.#, et al. MHC associations of ankylosing spondylitis in East Asians are complex and involve non-HLA-B27 HLA contributions. Arthritis Res. Ther. 22, 74 (2020).
7. Li, Z., Akar, S., Yarkan, H., et al. Genome-wide association study in Turkish and Iranian populations identify rare familial Mediterranean fever gene (MEFV) polymorphisms associated with ankylosing spondylitis. PLOS Genet. 15, e1008038 (2019).
8. Li, Z. & Brown, M. A. Progress of genome-wide association studies of ankylosing spondylitis. Clin. Transl. Immunol. 6, e163 (2017).
9. Li, Z., Haynes, K., Pennisi, D. J., et al. Epigenetic and gene expression analysis of ankylosing spondylitis-associated loci implicate immune cells and the gut in the disease pathogenesis. Genes Immun. 18, 135–143 (2017).
10. Li, Z., Yang, Y., Faraggi, E., Zhan, J. & Zhou, Y. Direct prediction of profiles of sequences compatible with a protein structure by neural networks with fragment-based local and energy-based nonlocal profiles. Proteins Struct. Funct. Bioinforma. 82, 2565–2573 (2014).
11. Li, Z., Yang, Y., Zhan, J., Dai, L. & Zhou, Y. Energy Functions in De Novo Protein Design: Current Challenges and Future Prospects. Annu. Rev. Biophys. 42, 315–335 (2013).